![]() suis and the secretion of suilysin (SLY), but it could significantly inhibit the hemolytic activity of SLY by directly binding to SLY and destroying its secondary structure. Studies found that apigenin did not affect the growth of S. In this study, we found, for the first time, that apigenin, as a flavonoid compound, could combine with ampicillin to treat severe S. Therefore, it is urgent to find a new strategy to relieve the damage caused by STSLS. STSLS is often accompanied by excessive production of inflammatory cytokines, which is the main cause of host death. ![]() suis) can cause a variety of diseases both in human and animals, especially Streptococcal toxic shock-like syndrome (STSLS), which commonly appears in severe S. ![]() As an important zoonotic pathogen, Streptococcus suis ( S.
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